Co-Director: Dr. Fernando Torrente
Co- Director: Marcelo Cetkovich-Bakmas
Mission of the Laboratory
To study the phenomena, dimensions, processes and psychopathological mechanisms that allow to improve the clinical characterization, diagnosis, etiological explanations and treatments of the psychiatric pictures in the context of psychiatric and neurological diseases, integrating the knowledge of clinical psychiatry, cognitive psychology And neuroscience.
Lines of investigation
The use of mathematical models for discourse analysis in patients with psychosis and bipolar disorders
Collaborative ongoing study with the Computer Department of the Faculty of Exact Sciences, CONICET
Psychopathological characterization and clinical delimitation of Attention Deficit Disorder and Hyperactivity (ADHD) in adults
Attention deficit disorder is the most commonly diagnosed problem in childhood and reliable studies show that more than half of people diagnosed in childhood continue to have this problem in adulthood. The presence of ADHD in adolescence and adulthood is associated with enormous functional consequences in the academic and work performance of those who suffer. Historically, ADHD has been defined by three types of symptoms: cognitive deficits (difficulties in attention and executive functioning), impulsivity and hyperactivity. However, its clinical characterization is currently incomplete, and its delimitation of other psychopathological entities is imprecise. This project seeks to: a) explore new symptomatic-etiological dimensions, such as motivational, affective-emotional and cognitive-behavioral alterations; B) to study their comorbidities in both axis I and axis II of the DSM-IV classification; C) to establish indicators that favor the differential diagnosis of other psychiatric pathologies that present symptomatic overlap, in particular, bipolar disorder and personality disorders.
Change of Personality in Dementias
The onset of dementia of different origin has been associated with changes in the personality traits of patients, beyond the presence of the specific symptoms that make up their diagnostic criteria. These changes in personality may appear subtly and early, and would be attributable to the alteration of the neural circuits that make up the biological basis of personality. The aim of this line of research is to study the phenomenon of personality change in a comparative manner in different dementia, using the NEO-PI-R personality questionnaire, and to establish different putative causal mechanisms.
Perception of disease, pharmacological adherence and affective temperament in bipolar disorder.
The way in which bipolar patients perceive their disease (perception of the disease) is a fundamental theoretical element of adherence to long-term drug treatment. It is also one of the core objectives of psychoeducational treatment, which has shown its efficacy in the prevention of new affective episodes in bipolar patients, as an adjunct to stabilizing pharmacological treatment. Despite their theoretical and practical importance, there are few studies about how bipolar patients naturally perceive their disease, and how this perception of the disease is related to other factors. In this line, the objectives of this study are: 1) to explore the natural perception of the disease of bipolar patients; 2) to submit to empirical contrast the theoretical relation between perception of the disease and pharmacological adherence; And 3) to explore the relationship between the perception of the disease and the affective temperament.
Affective temperament and affective psychopathology in epilepsy.
Affective symptoms are a common occurrence in patients with epilepsy, both in the form of comorbidity with depressive and bipolar syndromes, and in symptoms associated with the neurological picture itself. The concept of affective temperaments constitutes an element of interest to understand the predisposition of certain patients whose personality characteristics confer greater risk to develop comorbid affective pathology. Consequently, this line of research aims to highlight the presence of temperamental affective traits in patients with epilepsy and to establish the association between these traits and the presence of affective comorbidity, affective symptomatology, quality of life, perception of disease, pharmacological adherence and satisfaction with Antiepileptic treatment.
Depersonalization and anxiety
This line of research aims to study the symptoms of depersonalization and derealization in patients with anxiety disorders and community controls, determine possible